Definition of Respiratory System Disorders

Any disorder effects the respiratory system which includes the lungs, the bronchioles and the alveoli system. The respiratory system plays a vital role in delivering oxygen to the body — fuel for all the body's functions. It also removes carbon dioxide waste, eliminates toxic waste, regulates temperature, and stabilizes blood acid-alkaline balance (pH).

The lungs are the largest part of the respiratory system and have both "respiratory" and "non-respiratory" functions. The respiratory function involves gas exchange — the transfer of oxygen from the air into the blood and the removal of carbon dioxide from the blood. Non-respiratory lung functions are mechanical, biochemical, and physiological. The lungs provide a defense against bacterial, viral and other infectious agents; remove various metabolic waste products; control the flow of water, ions, and large proteins across its cellular structures; and manufacture a variety of essential hormones and chemical agents that have important biological roles.

Respiratory diseases can arise from a number of causes, including inhalation of toxic agents, accidents, and harmful lifestyles, such as smoking. Infections, genetic factors, and anything else that affects lung development, either directly or indirectly, can cause respiratory symptoms

(For more information: http://www.merckmanuals.com/professional/pulmonary_disorders.html)

ECR Center expedites every aspect of a pulmonology drug trial. It combines global experience in II, III and IV Phases of pulmonology drug development with expertise in respiratory system imaging, laboratory (including PK/PD and Biomarkers) IVRS, central data management, electronic data capture and regulatory issues. Our clinical trial experience includes the following pulmonology indications:

  • Acute Lung Injury
  • Airway Obstruction
  • Alpha 1-Antitrypsin Deficiency
  • Altitude Sickness
  • Asthma
  • Asthma, Aspirin-Induced
  • Asthma, Exercise-Induced
  • Asthma, Occupational
  • Bronchial Diseases
  • Bronchial Hyper reactivity
  • Bronchiectasis
  • Chronic Bronchitis
  • Bronchopneumonia
  • Common Cold
  • Cough
  • Dyspnea
  • Epistaxis
  • Hemoptysis