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Nephrology

Definition of Genitourinary System Disorders

We evaluate genitourinary disorders resulting in chronic kidney disease (CKD). Examples of such disorders include chronic glomerulonephritis, hypertensive nephropathy, diabetic nephropathy, chronic obstructive uropathy, and hereditary nephropathies. We also evaluate nephrotic syndrome due to glomerular dysfunction under these listings

  • Urology is the branch of medicine concerned with the urinary tract in both genders and the genital tract of the reproductive system in males.
  • Nephrology is the branch of medicine concerned with the kidney.

The urinary tract includes the organ system primarily responsible for cleaning and filtering excess fluid and waste material from the blood. The urinary system is made up of the following:

  • Kidneys
  • Ureters
  • Bladder
  • Urethra

The problems of the urinary system include acute and chronic kidney failure, urinary tract infections, obstructions along the urinary tract, and abnormalities present at birth. Diseases of the kidneys often produce temporary or permanent changes to the small functional structures and vessels inside the kidney. Frequent urinary tract infections can cause scarring to these structures leading to renal (kidney) failure. Some diseases that cause kidney damage include:

  • Glomerulonephritis
  • Hemolytic uremic syndrome
  • Polycystic kidney disease
  • Hydronephrosis
  • Urinary tract infections

(For more information go to: http://www.merckmanuals.com/professional/genitourinary_disorders.html)


ECR Center expedites every aspect of a renal system drug trial. It combines global experience in II, III and IV Phases of renal system drug development with expertise in renal system imaging, laboratory (including PK/PD and Biomarkers) IVRS, central data management, electronic data capture and regulatory issues. Our clinical trial experience includes the following renal system indications:

  • Acute Kidney Injury
  • Albuminuria
  • Azotemia
  • Diabetic Nephropathies
  • Cardio-Renal Syndrome
  • Adnexal Diseases